Clinical and Technical Aspects of Genomic Diagnostics for Precision Oncology

 | Post date: 2017/02/21 | 

Clinical and Technical Aspects of Genomic Diagnostics for Precision Oncology

The emergence of precision medicine has been predicated on significant recent advances in
diagnostic technology, particularly the advent of next-generation sequencing (NGS). Although the
chemical technology underlying NGS is complex, and the computational biology expertise required
to build systems to facilely interpret the results is highly specialized, the variables involved
in designing and deploying a genomic testing program for cancer can be readily understood and
applied by understanding several basic considerations. In this review, we present key strategic
decisions required to optimize a genomic testing program and summarize the technical aspects of
different technologies that render those methods more or less suitable for different types of
programs.
J Clin Oncol 35. © 2017 by American Society of Clinical Oncology



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